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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13
All Species:
24.24
Human Site:
S1218
Identified Species:
44.44
UniProt:
Q9UHV7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UHV7
NP_005112.2
2174
239318
S1218
F
P
K
S
G
V
I
S
N
W
V
R
V
E
E
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
S1232
F
P
K
S
G
V
I
S
N
W
V
R
V
E
E
Rhesus Macaque
Macaca mulatta
XP_001110128
2174
239364
S1218
F
P
K
S
G
V
I
S
N
W
V
R
V
E
E
Dog
Lupus familis
XP_537704
2182
240593
S1226
F
P
R
I
G
V
I
S
N
W
V
R
V
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q5SWW4
2171
238573
S1217
F
P
K
V
G
I
S
S
N
W
V
R
V
E
E
Rat
Rattus norvegicus
NP_001100505
2040
223488
D1112
E
H
G
R
Q
F
M
D
N
M
S
G
G
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
S1215
A
P
R
I
G
I
I
S
N
L
V
R
V
E
E
Chicken
Gallus gallus
XP_415884
2225
244861
S1269
I
P
K
V
G
A
V
S
N
L
V
R
V
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
P1162
T
V
L
E
E
Q
V
P
D
D
L
M
L
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
I1660
L
L
L
D
Q
C
S
I
I
Q
T
S
S
S
S
Honey Bee
Apis mellifera
XP_393643
1982
216109
E1054
S
V
L
E
L
L
R
E
Q
C
L
I
I
Q
S
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
V1719
S
E
Y
I
L
S
H
V
D
A
L
E
L
L
M
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
A199
N
S
P
Y
A
T
L
A
R
L
A
G
C
V
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.8
97.7
94.1
N.A.
92.5
87.8
N.A.
89.5
84.6
N.A.
64.8
N.A.
24.7
35
21
25.7
Protein Similarity:
100
98.3
98.4
96
N.A.
96.4
91.2
N.A.
94
90.5
N.A.
76.9
N.A.
41.3
51.5
37.4
36
P-Site Identity:
100
100
100
86.6
N.A.
80
6.6
N.A.
66.6
66.6
N.A.
0
N.A.
0
0
0
0
P-Site Similarity:
100
100
100
93.3
N.A.
86.6
20
N.A.
80
73.3
N.A.
26.6
N.A.
0
26.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
8
0
8
0
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
8
0
0
8
0
0
% C
% Asp:
0
0
0
8
0
0
0
8
16
8
0
0
0
0
0
% D
% Glu:
8
8
0
16
8
0
0
8
0
0
0
8
0
54
54
% E
% Phe:
39
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
8
0
54
0
0
0
0
0
0
16
8
0
0
% G
% His:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
8
% H
% Ile:
8
0
0
24
0
16
39
8
8
0
0
8
8
0
0
% I
% Lys:
0
0
39
0
0
0
0
0
0
0
0
0
0
8
0
% K
% Leu:
8
8
24
0
16
8
8
0
0
24
24
0
16
16
8
% L
% Met:
0
0
0
0
0
0
8
0
0
8
0
8
0
0
8
% M
% Asn:
8
0
0
0
0
0
0
0
62
0
0
0
0
0
0
% N
% Pro:
0
54
8
0
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
16
8
0
0
8
8
0
0
0
8
0
% Q
% Arg:
0
0
16
8
0
0
8
0
8
0
0
54
0
0
0
% R
% Ser:
16
8
0
24
0
8
16
54
0
0
8
8
8
8
16
% S
% Thr:
8
0
0
0
0
8
0
0
0
0
8
0
0
0
0
% T
% Val:
0
16
0
16
0
31
16
8
0
0
54
0
54
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
39
0
0
0
0
0
% W
% Tyr:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _